Prolonged Epstein-Barr Virus Infection with Chronic Fatigue in Young Adult
Case at a Glance
A 24-year-old Caucasian male presents with persistent fatigue lasting 5 months following Epstein-Barr virus (EBV) infection, seeking evaluation of alternative treatment options including ultraviolet blood irradiation therapy.
Patient's Story
The patient is a previously healthy 24-year-old male (height 5'9", weight 180 lbs) who developed extreme fatigue approximately 5 months ago in association with laboratory-confirmed EBV infection. Despite implementing conservative management strategies including adequate rest, proper hydration, and nutritional optimization, his fatigue symptoms have persisted significantly. The patient expresses frustration with his prolonged recovery and is actively seeking additional therapeutic interventions. He specifically inquires about ultraviolet blood irradiation therapy (UVBI) as a potential treatment modality.
Initial Assessment
Physical examination reveals a well-appearing young adult male with no acute distress. Vital signs are stable. The patient reports persistent fatigue as his primary complaint, with no fever, lymphadenopathy, or hepatosplenomegaly at the time of evaluation. Laboratory workup confirms previous EBV infection with appropriate serologic markers.
The Diagnostic Journey
Initial presentation 5 months prior included typical infectious mononucleosis symptoms with positive EBV serology. Standard supportive care was initiated with expectation of gradual improvement. However, the patient's fatigue has remained significantly debilitating, prompting consideration of post-viral fatigue syndrome or chronic EBV complications.
Final Diagnosis
Post-viral fatigue syndrome secondary to Epstein-Barr virus infection; Chronic fatigue following infectious mononucleosis
Treatment Plan
Continued supportive care with emphasis on gradual activity progression, sleep hygiene, and stress management. Patient education provided regarding evidence-based treatments versus unproven alternative therapies. Consultation with infectious disease specialist considered for persistent symptoms beyond typical recovery timeframe.
Outcome and Follow-up
Patient counseled that ultraviolet blood irradiation therapy lacks scientific evidence for EBV treatment and is not recommended by medical guidelines. Focus redirected toward established supportive measures and monitoring for gradual improvement. Regular follow-up scheduled to assess symptom progression and consider additional interventions if needed.